Licorice and Men’s Health: A Natural Ally for Middle-Aged Vitality

Licorice, derived from the Glycyrrhiza glabra root, has been used in traditional medicine for thousands of years, from ancient Chinese herbal formulas to Greek medicinal recipes. But today, modern science is increasingly validating its value—especially for middle-aged men, who face health challenges like hormonal changes, inflammation, prostate issues, and stress-related conditions. This review dives deep into the science-backed benefits of licorice, safe ingestion methods, and its potential role in male health optimization.

🧠 1. Hormonal Support and Testosterone Balance

Licorice contains active compounds such as glycyrrhizin and glabridin, which may affect hormone regulation. Some studies have raised concerns about licorice’s potential to lower testosterone due to its effect on 17β-hydroxysteroid dehydrogenase and aromatase enzymes [NIH]. However, this effect is dose-dependent and more likely when consuming large amounts of glycyrrhizin-rich licorice.

On the flip side, deglycyrrhizinated licorice (DGL), which has the glycyrrhizin removed, may offer anti-inflammatory benefits without impacting testosterone levels negatively. Therefore, licorice may still support endocrine balance when consumed moderately and wisely.

❤️ 2. Cardiovascular Health Benefits

Middle-aged men are at increased risk of cardiovascular issues due to rising blood pressure and cholesterol. Licorice has demonstrated antioxidant and vasodilatory effects that can support healthy blood flow and reduce oxidative stress.

One study showed that licorice extract helped lower LDL cholesterol and improve blood vessel elasticity, contributing to heart health—especially in men over 40 who are beginning to experience early signs of cardiovascular decline.

🧴 3. Prostate Health and Anti-Inflammatory Effects

Licorice’s potent anti-inflammatory properties may help alleviate symptoms associated with benign prostatic hyperplasia (BPH) and chronic prostatitis, two common prostate conditions in middle-aged men.

Animal studies and in vitro research have revealed that glabridin and licochalcone A—two active flavonoids in licorice—suppress pro-inflammatory cytokines like IL-6 and TNF-α, which are implicated in prostate inflammation[ScienceDirect].

🛡️ 4. Immune System and Stress Resilience

Middle-aged men often experience declining immune resilience, especially under chronic stress. Licorice functions as an adaptogen—a natural substance that helps the body resist stress. It supports the adrenal glands and enhances cortisol balance, particularly through compounds like glycyrrhetinic acid, which mimics the effects of cortisol in moderation [National Library of Medicine].

This effect can help men handle work-related burnout or physical fatigue more effectively—especially when paired with other adaptogens like ashwagandha.

🧃 Ingestion Methods

✅ 1. Licorice Root Tea

A gentle daily option, especially effective in DGL form.
Ideal for gastrointestinal support and general vitality.
Preparation: Steep 1 tsp of dried root in hot water for 5–10 minutes.

✅ 2. Licorice Supplements (Capsules or Tablets)

Available in standardized extracts, including DGL for those avoiding glycyrrhizin.
Always follow the manufacturer’s dosage instructions.

✅ 3. Licorice Lozenges (DGL)

Often used for acid reflux and gut health without affecting blood pressure or hormones.

⚠️ Caution

Avoid long-term use of high-glycyrrhizin licorice, especially for those with high blood pressure, low potassium, or kidney issues. Limit to less than 100 mg/day of glycyrrhizin unless supervised by a healthcare provider [Mayo Clinic].

📌 Conclusion

Licorice offers a versatile, natural supplement that can support the hormonal, cardiovascular, prostate, and stress-related health concerns that often arise in middle-aged men. However, proper dosing and form selection—especially choosing DGL when appropriate—is essential to maximize the benefits and minimize risks. As always, consult a healthcare professional before incorporating licorice into your daily regimen.

Licorice and Men’s Health: A Natural Ally for Middle-Aged Vitality